Incidence of two virulence factors (aerobactin and mucoid phenotype) among 190 clinical isolates ofKlebsiella pneumoniaeproducing extended-spectrum β-lactamase

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Virulence factors (aerobactin and mucoid phenotype) in Klebsiella pneumoniae and Escherichia coli blood culture isolates.

We examined the presence of two virulence factors in 241 blood isolates of Klebsiella pneumoniae from patients hospitalized during 1989 and 1990 in 7 French hospitals, and 125 blood isolates of Escherichia coli from one hospital. Aerobactin was scored phenotypically and genotypically with an intragenic DNA probe of 2 kb. The mucoid phenotype was assessed by culture on trypticase soy agar and by...

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High Prevalence of CTXM-15 Type Extended-Spectrum Beta-Lactamase Among Clinical Isolates of Klebsiella Pneumoniae

Background: Production of β–lactamases by enterobacteriacea, especially Klebsiella pneumoniae, is one of the emerging health problems in the world. The purpose of this study was to assess the frequency of blaCTX-M15 gene in K. pneumoniae isolates and determine the molecular diversity of CTXM producing isolates. Methods: In...

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Extended – Spectrum β-Lactamase Producing Klebsiella Species among Clinical Isolates

Extended – Spectrum Βeta-Lactamase producing strains among clinical isolates has been steadily increasing over the past years. Microorganisms responsible for UTIs such as Escherichia coli and klebsiella 5pp have the ability to produce ESBLs in large quantities. All the strains of klebsiella species in this study were collected from routine clinical samples confirmed by biochemical and other tes...

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Association between Virulence Factors and Extended Spectrum Beta-Lactamase Producing Klebsiella pneumoniae Compared to Nonproducing Isolates

Klebsiella pneumoniae is considered an important opportunistic multidrug-resistant pathogen. Extended spectrum β-lactamases (ESBLs) and expression of a multitude of virulence factors may work in a harmony resulting in treatment failure. This study was undertaken to compare the virulence characteristics and genetic relatedness between ESBL and non-ESBL producing K. pneumoniae. Methods. Antibioti...

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Detection of SHV type Extended-Spectrum B-lactamase and Risk Factors in Pseudomonas aeruginosa Clinical Isolates

OBJECTIVE Pseudomonas aeruginosa is one of the most important causes of nosocomial infections and can acquire resistant to many antimicrobials, including β-lactams. The aim of this study was to detect the prevalence of SHV type extended-spectrum beta-lactamase (ESBL), antimicrobial resistance patterns of the P. aeroginusa and risk factors in hospitalized patients in two teaching hospitals in Sa...

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ژورنال

عنوان ژورنال: FEMS Microbiology Letters

سال: 1992

ISSN: 0378-1097,1574-6968

DOI: 10.1111/j.1574-6968.1992.tb05384.x